Green tea

June 14, 2012
Green Tea (camellia sinensis) Health Benefits Green tea is composed from the plant species Camellia sinensis, which is found in China and Southeast Asia, and is now grown across the globe. It has been used regularly for thousands of years and has many observed benefits to health. Among a selection chemicals it can contain Vitamin C, and minerals such as selenium or zinc. Green tea may decrease blood pressure, and thus can play an essential role in the addressing of cardiovascular disease. Research and clinical trials show that it can reduce cholesterol by affecting the way it is absorbed in the gut. It may also alter positively glucose tolerance and insulin sensitivity. Regular consumption of green tea may also sufficiently reduce the risk of breast cancer. Also, it has been pointed out that epigallocatechine gallate (EGCG) possessed within green tea can assist the immune system by raising the number of T-cells in the body. Safety Toxic results may be attained with the use of green tea extract, as there have been observed reports of liver damage. It is recommended that you adhere to the dosing information of any extract that you may use, and to not take on an empty stomach. Drug Interactions A study suggested that EGCG in green tea may make the anticancer drug bortezomib ineffective.

Magnesium for anxiety

June 13, 2012
Magnesium Health Benefits Magnesium is an important mineral nutrient and is found in each cellular type. More than 300 enzymes require the use of magnesium ions for their catalytic functions, and it is needed in a lot biological functions, not discounting regulatory behaviour involved with DNA synthesis. As it is required for Adenosine-triphosphate (ATP) to function, it is thus important to celluar operation, playing an indispensable function in accomodating the cells of the body with their most vital source of energy. It is very regular for us not to achieve acceptable levels of magnesium in our daily diet. Insufficient supply is commonly associated with muscle spasms, anxiety, depression, cardiovascular disease, diabetes, migraines, osteoporosis and high blood pressure. Indeed, it is normally a prescribed supplement for fighting Treatment Resistant Depression, after it being shown that people who attempt suicide with TRD commonly have low levels of magnesium in their cerebral spinal fluid. Recommended Daily Dosage 300-400mg per day The most normal sign of an large intake of magnesium is diarrhoea, and thus it is advocated to drastically decrease your dose until this works.

Coconut oil

June 13, 2012
Coconut Oil Health Benefits Coconut oil has been suggested to hold a range of health benefits. These differ from helping in weight-loss, combating heart disease, and the observed anti-fungal and anti-microbial activity. And it aids the brain with a highly worthwhile energy source. Coconut oil has found common use as a beauty product in recent years. When applied to the skin and hair, coconut oil has a moisturizing outcome, and may also have a part to play in reducing hair loss through the application of lauric acid, a microbial agent found in coconut oil. The fatty acids existing in coconut oil may also help to combat dandruff. Coconut oil is commonly spotted in cosmetic products more and more due to these proclaimed boons. Few big studies have been conducted into the benefits of coconut oil, with the huge majority of studies being meager and uncontrolled. Despite this, research has pointed out several areas where coconut oil may be advantageous, although this research is still deficient. For example, it has been shown that coconut oil can be applied as a spray for the fighting of head lice in children. Preliminary studies have highlighted that it can be as convincing as chemical solutions containing insecticides, but no large studies have been conducted. Maybe ironically, some people use coconut oil as a aid for weight loss in defiance of its high calorific attributes. Studies have yet to be run on a great scale, but developing research has found that 10 ml coconut oil three times a day may perhaps reduce waist size after 1-6 weeks of use. There is also documented assistance in taking coconut oil as a medication for Alzheimer's disease, diabetes, chronic fatigue, Crohn's disease, irritable bowel syndrome, and thyroid syndrome. No large test has been conducted in these subjects, but some tests are continuing. There are a few considerations that coconut oil may raise levels of cholesterol in the body, however tests so far suggests that coconut oil might raise the levels of "good" cholesterol in the body whilst having no consequence upon the levels of "bad" cholesterol. Recommended Daily Dosage No academic treatment dosage at the moment prevails, and serving routines of vitamin companies and scientists often vary greatly. 4g of coconut oil looks to be a common starting point, but common sense says that if one is to further increase the dose it should be done carefully as experience allows.

Getting fit the easy way

June 12, 2012
Based on the large number of over-tired parents of littlel children out there, it is usually assumed that these children are constantly on the move. However, research has found that children are sedentary 73 to 84 per cent of the time that they are awake. Additionally, even though we know that "screen time" can have many detrimental effects on child development both physically and socially, most children are now exposed to "screen time" too young in life and for far too long. The Canadian Society for Exercise Physiology (CSEP) and ParticipACTION released Canada's first ever physical activity guidelines for the early years. Basically, the guidelines state that all children aged four and under should be moving more and sitting less throughout the day. The following guidelines are based on research of sedentary behaviours of children and are supported by the Children's Hospital of Eastern Ontario Research Institute, Healthy Active Living and Obesity Research Group (CHEO-HALO). It's time for all babies to learn how to workout maybe they need an online personal trainer


June 10, 2012
Mechanism of Picamilon Picamilon is a molecular combination of vitamin B3 and gamma-aminobutyric acid (GABA). Supplemental GABA has little to no active bioavailability where as picamilon's unique composition allows it to readily cross the blood brain barrier and affect a number of changes. Inside the brain Picamilon increases intra-cranial and cortical blood flow and acts as potent vasodilator many times more powerful than Hydergine or Vinpocetine. Due to its GABA affiliation picamilon also acts as a mild sedative, calming the nerves and reducing symptoms of anxiety and irritability. Uses Picamilon's vasodilative properties improve cerebral blood-flow and thus cerebral metabolism and oxygenation May benefit mild depression Lowers LDL levels At higher doses may function as a mild stimulant May be of particular use to those suffering social anxiety disorder May exhibit stimulant type effects at higher doses Issues At higher doses Vitamin b3 (2g+) has been indicated in liver damage and may cause flushing and skin irritations. Whilst unsubstantiated - cessation of picamilon after a long-term/high dose regime may increase the risk of seizures and exhibit many of the severe withdrawal symptoms associated with benzodiazepines. Dosage There is little official medical stricture regarding picamilon's ideal dose regime, however, at smaller doses, picamilon displays an exclusive non-drowsy sedative effect, whilst at higher doses, (some 100mg three times daily) picamilon develops a stimulant type affinity and user's should tailor their dose according to their specific goals.


June 6, 2012
Image this scene: There is a company conference the next day along with your Japan provider. This particular conference demands that you simply maintain best type for many essential discussions. There are several reviews to debate, numerous details in order to remember, and also most importantly you need to acquire some relax. The best? Making a stop in p shop, obviously. A gathering such as this is a lot as well necessary to undertake with no fine-tuning your own biochemistry and biology. You have to develop the perfect neurochemical circumstances regarding studying as well as creativeness. Anyone asks the particular druggist, who also after that factors a person towards rack associated with intellectual improvement substances. A person kit your own container along with containers associated with piracetam, vasopressin, hydergine, choline, DMAE, and perhaps just a little centrophenoxine. Right after being released on the house, and also taking suitable dosages of every of such you decide to go into the research to slide in your cranial electric powered signalgeber together with your lighting as well as audio gadget. You already know from the encounter which of numerous innovators within the awareness trend this specific mixture of chemical substances as well as mind devices includes a synergistic impact which will produce the perfect psychobiological condition for your duties which lay forward. You may be sure your own Japan equivalent tend to be done an identical way. Right after one hour inside your research you are feeling completely different. You might be comfortable, however notify and also innovative. Your own brainwave exercise offers changed, as well as a ELEKTROENZEPHALOGRAPHIE would certainly display it is becoming much more normal and it has improved within extravagance in some eq, making you feel at the same time in a big way peaceful but inside a condition associated with extreme focus, reduce and also innovative along with psychologically fast and also notify. The brain-mapping gadget might display how the 2 hemispheres of the human brain had been inside a condition associated with "superconnection, " having an tremendous embrace the quantity of details moving involving the hemispheres. Simultaneously, the pace associated with as well as the power amount of your mind cellular material offers dramatically improved. You happen to be today within the ideal condition in order to imprint brand new thoughts, in order to strategy brand new and much more innovative methods, in order to aesthetically practice all the details of the forthcoming conference...use a nootropic


June 4, 2012
I've provided support for multiple concurrent mobiles. Now when you plug in more than one phone, each device will appear up in a combo box. You can highlight the device and the currently selected device's ECID will fill in in the ECID field and the real default firmware will be choosen appropriate to the device. I've also made some huge alterations to the underlying framework under the hood. In doing so I've contributed a few new features. First, the links that show up in the console are now clickable. This means when you pastebin your log file you can click on the link and it'll open in your customt browser. Also when you save your shsh file you will see a 'Click here to Open' link that, when clicked, will open Finder (OSX) or Explorer (WIN) to the SHSH file saved. No more whining about where the files are saved. (Not that any of you have any reason to tinker with the files outside of backing up the entire directory right?) :) Also, the list of files that show up in the console when you 'Display SHSH' are also clickable and will reveal themselves in Finder/Explorer as well. I've made some performance tweaks as well so the app should be slightly quicker. Lastly, I have added some much needed feedback to the console when saving SHSHs. The messages are quite verbose and explain much more plainly the situation if you are unable to get SHSHs because your device is 'not eligible'. I'm working on some more features for future jailbreak releases. Thanks for your comments!


May 27, 2012
Mechanism L-Tyrosine is an amino acid metabolite metabolized by the enzyme Tyrosine Hydroxylase into Levodopa and subsequently Dopamine and norepinephrine (both possible nootropic chemicals). Dopamine and norepinephrine antagonists, reuptake inhibitors and precursors have been known to enhance concentration, focus, and most importantly working memory and executive function via chemical signalers in the prefrontal cortex; the full spectrum of dopamine and norepinephrine functionality still remains unknown. Uses So, what are the benefits of L-Tyrosine exactly? Increased libido through elevated plasma neurotransmitter levels Decreased stress levels through regulation of cortisol production Increased drive and focus Improved working memory and executive function May improve symptoms of depression Issues Although this amino acid seems at first to be a functional nootropic and a typical way of increasing plasma neurotransmitter concentrations - there a number of complexities in its consumption. L-tyrosine in its unadulterated form lacks significant bioavailability - with a large % of it being lost in the digestive system. L-tyrosine also competes poorly in intestinal absorption against other amino acids. Elevated brain-dopamine levels compete for absorption with serotonin and may trigger mild symptoms of depression. A significant portion of L-tyrosine is deanimated in first-pass hepatic metabolism through the MAO-A/B enzymes. Dosage The University of Maryland Medical Center specifies 500mg-1500mg of L-tyrosine up to thrice occasions daily for the relief of hardship and anxiety (and potentially as a nootropic). I would recommend ingestion on an empty stomach, with a carbohydrate drink coupled with vitamin C and a B vitamin complex for maximum absorption. For the expert consumer, the purchase of Acetyl-l-tyrosine is preferred due to its greater stability, bioavability and lower doses (250mg per dose) My experience My l-tyrosine experiences were mainly negative, but this is not to say they will be for you. I believe I am deficient in serotonin and hence increased levels of dopamine lead to anxiety. L-tyrosine at 500mg three times daily increased my motivation levels, but also exposed me to significantly increased anxiety, and rebound depression some 3-4 hours after an initial dosing. All in all I would not recommend this amino-acid to those with a similar neurological disposition to my own.Still... this nootropic agent may be more suitable for you. So go ahead and add it to your nootropics stack and leave feedback!


May 27, 2012
Mechanism Vinpocetine is a slightly synthetic alkaloid created from vincamine an extract of the periwinkle genus. In double-blind placebo research Vinpocetine has been shown to boost cerebral blood-pumo, and act as a powerfult neuroprotective agent. Due to its significant cerebral vasodilative powers, Vinpocetine may assist brain functions such as focus and memory by activating cerebral metabolism. In Asia it has been used in various forms to helpt cerebrovascular disorders and age-related memory impairment and has recently been indicated in the treatment of Alzheimer's disease due to its potent anti-inflammatory properties. Uses Significant memory enhancement Potential body-wide vasodilator (handy for you body builders looking for increased blood-flow) Improves focus and mental clarity Clinically proven neuroprotective qualities. Anti-inflammatory Vinpocetine is biologically active in minute quantities, with the beginning recommended dose being a tiny 5mg daily; once hypersensitivity is ruled out, one may up the quantity to between 10-40mg daily. I have noticed a number of side-effects with this chemical and so I particularly feel it important to establish them, as follows: Indigestion, nausea, dizziness, anxiety, facial flushing, insomnia, headache, drowsiness and xerostomia (dry mouth) Vinpocetine may also produce a temporary drop in blood pressure. Out of the above I have personally experienced xerostomia(dry mouth) facial flushing and brief periods of anxiety. So, with its high side-effect profile, is this really a nootropic worth supplementing? In my personal opinion, hell yeah! The mental clarity I experience is second to none. If your brain could take the most invigorating, cleansing shower it had ever experienced, then, the water would be vinpocetine without a doubt; I also appreciate higher degrees of visual clarity and wakefulness - sadly I've forgotten if it improved my memory ;) Can this truly potent and useful chemical be purchased easily and discounted? It is available over the counter in numerous vitamin stores around the world and of course from a lot of online retailers (check out Swanson for great details) A month's supply, at 30mg daily will cost you roughly $8 or $2 a week or 0.285 cents a day... or... you get the message :) All in all, a must buy for anyone looking for improved mental performance and general neuroprotection as they age.

smartdrugs and nootropics

May 24, 2012
Introduction Just what is Idebenone? Those ofus who have inquired into this substance will see that the internet is awash with all manner of bizarre and fascinating claims; a more advanced version of coq10 is a common claim, a more biologically available version of coq10 another - one site even purports (not a surprise since they sell just coq10) that idebenone is a synthetic, Indian chemical totally unrelated to coq10 and intrinsically dangerous. Confused? Wonder if this chemical is indeed a nootropic? Smartnootropics to the rescue. Mechanism Idebenone is a short-chain quinone in comparison to coq10 a long chain quinone and as such possesses both superior bioavailability and a faster peak plasma concentration profile. Idebenone is a potent antioxidant which is currently being investigated for its therapeutic role in neuromuscular disorders and unlike coq10 has demonstrated an ability to renew cellular ATP levels in abnormal conditions through cytosolic-mitochondrial shuttling. Idebenone also increased learning and memory in mice studies and has been claimed to activate NGF in the human brain. Finally Idebenone has been shown to uprate the production of the life-extending enzyme: superoxide dismutase in specific cortical regions. Uses May benefit neuromuscular disorders Improves memory and learning and may increase brain dopamine levels Has been indicated to accelerate the turn over of the neurotransmitter serotonin. Powerful antioxidant May improve age related mitochondrial decline Increases production of superoxide dismutase Issues At high doses idebenone has demonstrated an ability to cause cellular death via genomic DNA fragmentation, however the study dose would be near impossible to match in-vivo and lower doses exhibited no such toxicity. Idebenone has also been theorised to stimulate oxygen radical production in mitochondrial electron transport and some now label it a "pro-oxidant" capable of accelerating the aging process - it is unclear whether its antioxidant profile and production of superoxide dismutase are sufficient to counteract this process or whether an additional antioxidant (ALA) could sufficiently nullify idebenone's pro-oxidant capacity. Dosage Idebenone is well tolerated and doses range from a mere 70mg up to 200mg or greater. As always one should err on the side of caution and begin with an allergy test. Experience I cannot attest to Idebenone's antioxidant capacity. From a single 150mg dose daily for a week I experienced a noticeable increase in energy and positivity; the type I would normally associate with an uprating of the neurotransmitter serotonin. No side effects were noted. Should this chemical be added to your list of nootropics? Given the potential dangers I would sadly conclude that this is a nootropic to AVOID.

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